Istvan Nagy Selected Research

TRPV Cation Channels

7/2019	TRPV1 Antagonists as Novel Anti-Diabetic Agents: Regulation of Oral Glucose Tolerance and Insulin Secretion Through Reduction of Low-Grade Inflammation?
4/2014	Prolonged exposure to bradykinin and prostaglandin E2 increases TRPV1 mRNA but does not alter TRPV1 and TRPV1b protein expression in cultured rat primary sensory neurons.
1/2007	Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.
12/2004	Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis.
11/2003	Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons.

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Istvan Nagy Research Topics

Disease

16	Pain (Aches) 01/2022 - 11/2003
9	Inflammation (Inflammations) 06/2021 - 03/2009
7	Hyperalgesia 01/2020 - 06/2003
6	Burns 10/2021 - 08/2011
4	Wounds and Injuries (Trauma) 11/2021 - 07/2011
3	Cystitis 01/2020 - 12/2004
3	Hereditary Angioedemas 07/2010 - 09/2004
2	Chronic Pain 01/2018 - 01/2011
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Amyloidosis 01/2021
1	Memory Disorders (Memory Loss) 01/2021
1	Shock 01/2021
1	Disease Progression 01/2021
1	Sepsis (Septicemia) 01/2021
1	Endotoxemia 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Melanoma (Melanoma, Malignant) 10/2019
1	Neoplasms (Cancer) 04/2017
1	Nasopharyngeal Carcinoma 04/2017
1	Neoplasm Metastasis (Metastasis) 04/2017
1	Dehydration (Water Stress) 02/2013
1	Acute Pain 05/2012
1	Acne Vulgaris 07/2011
1	Neuralgia (Stump Neuralgia) 01/2011
1	Peripheral Nerve Injuries 03/2009
1	Type 2 Diabetes Mellitus (MODY) 01/2007
1	Hyperglycemia 01/2007
1	Hemorrhagic Cystitis 12/2004
1	Abnormal Reflex (Hyperreflexia) 12/2004
1	Hyperinsulinism (Hyperinsulinemia) 11/2003

Drug/Important Bio-Agent (IBA)

5	Ion Channels (Ion Channel)IBA 10/2021 - 06/2010
5	Capsaicin (Zostrix)FDA Link 10/2020 - 01/2007
5	TRPV Cation ChannelsIBA 07/2019 - 11/2003
4	Analgesics (Analgesic Drugs)IBA 01/2022 - 01/2011
4	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2018 - 07/2010
3	Histones (Histone)IBA 11/2021 - 01/2017
3	CarrageenanIBA 06/2021 - 01/2017
3	LipopolysaccharidesIBA 01/2021 - 07/2011
3	CannabinoidsIBA 10/2020 - 07/2010
3	EndocannabinoidsIBA 01/2020 - 03/2009
3	anandamide (arachidonylethanolamide)IBA 01/2020 - 06/2003
3	EnzymesIBA 06/2017 - 03/2009
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 04/2017
2	CalciumIBA 10/2020 - 06/2017
2	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 01/2020 - 03/2009
2	Messenger RNA (mRNA)IBA 01/2020 - 10/2008
2	Cytostatic AgentsIBA 10/2019 - 04/2017
2	Glucose (Dextrose)FDA LinkGeneric 07/2019 - 01/2007
2	Serine (L-Serine)FDA Link 01/2018 - 01/2017
2	Mitogen-Activated Protein Kinase 3IBA 01/2018 - 08/2011
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2008 - 12/2004
1	Untranslated RNA (Noncoding RNA)IBA 01/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2021
1	BU 224IBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	LigandsIBA 01/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021
1	Cyclophilins (Cyclophilin)IBA 01/2021
1	ImidazolinesIBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021
1	Imidazoline ReceptorsIBA 01/2021
1	Dipyrone (Metamizole)IBA 10/2020
1	Dinoprostone (PGE2)FDA Link 10/2020
1	AmpyroneIBA 10/2020
1	LeptinIBA 01/2020
1	URB937IBA 01/2020
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2020
1	CytokinesIBA 01/2020
1	Chemokine CX3CL1IBA 01/2020
1	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2019
1	Uric Acid (Urate)IBA 01/2019
1	1,2- dioleoyl- sn- glycero- 3- phosphoethanolamine- N- arachidonoylIBA 01/2018
1	2- (2- chlorophenyl)- 3- (4- chlorophenyl)- 7- (2,2- difluoropropyl)- 6,7- dihydro- 2H- pyrazolo(3,4- f)(1,4)oxazepin- 8(5H)- oneIBA 01/2018
1	Voltage-Gated Sodium ChannelsIBA 01/2018
1	Morphine (MS Contin)FDA LinkGeneric 01/2018
1	N- (3- methoxyphenyl)- 4- chlorocinnamanilideIBA 01/2018
1	1-dodecylpyridoxal (PLD)IBA 06/2017
1	MicroRNAs (MicroRNA)IBA 04/2017
1	ElementsIBA 02/2013
1	Carrier Proteins (Binding Protein)IBA 02/2013
1	Acyl-CoA OxidaseIBA 02/2013
1	Proteins (Proteins, Gene)FDA Link 07/2011
1	XenonIBA 01/2011
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2011
1	Acid Sensing Ion ChannelsIBA 03/2010
1	Freund's AdjuvantIBA 03/2009
1	capsazepineIBA 12/2004
1	Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)IBA 11/2003
1	Insulin ReceptorIBA 11/2003
1	Insulin (Novolin)FDA Link 11/2003

Therapy/Procedure

3	Therapeutics 07/2010 - 09/2004
1	Subcutaneous Injections 01/2020
1	Drug Therapy (Chemotherapy) 04/2017
1	Analgesia 01/2011
1	Ligation 01/2011